There is the use of energy restriction mimetic agents (ERMAs) to selectively target cancer cells which are addicted to glycolysis and could be a promising therapeutic approach.
Thiazolidinediones (TZDs) are synthetic agonists of peroxisome proliferator-activated receptor (PPAR)γ that were developed to treat type II diabetes.
These compounds also display anticancer effects which appear mainly to be independent of their PPARγ agonist activity but the molecular mechanisms involved in the anticancer action are not yet well understood. Results obtained on ciglitazone derivatives, mainly in prostate cancer cell models, suggest that these compounds could act as ERMAs.
2-Deoxyglucose as an energy restriction mimetic agent: effects were on mammary carcinogenesis and on mammary tumor cell growth in vitro.
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the dysregulation of hormones may affect several pathways and processes in their body, which leads to risk in the emerging possibility for type ii diabetes, cardiovascular disease, infertility.
The most prevalent hormonal illness, polycystic ovarian syndrome, mostly affects adolescent girls as their hormonal balance and menstrual regularity mature.
Anovulation, dysmenorrhea, and amenorrhea are caused by the variability of menstrual hormones and other causes.The dysregulation of hormones may have an impact on a number of physiological pathways and functions, increasing the risk of type II diabetes, cardiovascular disease, and infertility.Genetics, neuroendocrine, lifestyle/environment, and obesity are among the risk factors that predispose people to PCOS. The pathophysiology of PCOS primarily focuses on hormonal disruption, insulin resistance, and hyperandrogenism causing poor folliculogenesis and increasing the risk of related comorbidities such endometrial cancer and type II diabetes.The explanation of potential treatments for controlling the syndrome coupled with lifestyle adjustment, which can be used singly or in combination depending on the symptoms.
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Your question seems incomplete, please find the complete question below:
Discuss the effects of hormonal dysregulation in humans.
What type of infection is transmitted by athlete’s foot?
Bacterial
Fungal
Parasitic
Viral
Answer:
Fungal
Explanation: took the test!! :)
Fungal, Because the athlete's foot is a fungus, and is transmitted to an athletes foot. Hope it helps
Some researchers use fmri technology to study activity in the brain. What is the underlying activity detected by fmri?.
Some researchers use fMRI technology to study activity in the brain. The underlying activity detected by fMRI is by measuring the changes occurring in both oxygen amount present in the blood as well as the blood flow amount.
fMRI technology helps to detect the activity of the brain by measuring the changes occurring in both the amount of oxygen present in the blood as well as the amount of blood flow. This measurement is termed as the activity depending on the blood-oxygen level or called BOLD activity.
Functional magnetic resonance imaging or fMRI measures the activity of the brain by detecting various changes associated with the flow of blood. This technique will be relying on the fact of coupled activity of cerebral blood flow as well as neuronal activation. When an area of the brain is used up, there will be an increase in blood flow to that region.
The primary fMRI form uses contrast which is blood-oxygen-level dependent. This is a specialized brain type and a body scan that is used to map the activity of neurons in the brain or the spinal cord present in humans or in other animals by imaging the hemodynamic response which is related to the use of energy by the brain cells.
fMRI has come to dominate the mapping research of the brain as it does not involve injection uses, surgery, the ingestion of substances, and ionizing radiation exposure. This measure is usually corrupted by noise which is from various sources most frequently. Hence, the underlying signals are extracted by statistical procedures.
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What must occur for protein translation to begin?
explain why bacteria, in particular, are very useful organism in the process of genetic engineering
Answer: The bacterial cells are being used in order to create genes and produce human insulin. The bacteria is used to make protein, which is a good thing. I hope this at least helped, and I believe this is why bacteria is useful organism in the process of genetic engineering.
Serotonin and Dopamine are 2 of the many neurotransmitters that are released when a synapse occurs.
A) true
B) False
Answer:
it is true
Explanation:
which of the following is a function of the nucleus.
stores sugar
packages proteins
stores dna
builds proteins.
Answer:
Stores DNA.
Explanation:
The nucleus is the control center of the cell.
__are to ribosomes as lipids are to__
A) Sugars; peroxisomes
B) Carbohydrates; rough endoplasmic reticulum
C) Nucleoli; lysosomes
D) Proteins; smooth endoplasmic reticulum
Proteins are to ribosomes as lipids are to smooth endoplasmic reticulum. Details about functions of organelles can be found below.
What are organelles?Organelles are specialized structures in the cells of living organisms that perform specific functions in the cell.
Examples of organelles are as follows:
RibosomeNucleusEndoplasmic reticulumVacuolesMitochondriaHowever, ribosomes are involved in the synthesis of proteins while the smooth endoplasmic reticulum are directly involved in the synthesis of lipids.
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the chemical formula for water is
Answer: The chemical formula for water is H2O!
Answer:
H2O
Explanation:
H2O
Decomposers, detrivores, and scavengers feed on dead organic material. How are decomposers different from scavengers and detrivores?.
Answer:
Okay, so a detrivore is a type of decomposer.
Basically, scavengers eat their food while decomposers do not eat the food, but instead break it down further externally.
The difference between a decomposer and the scavenger is that the scavenger is the one that consumes dead plants, animals or carrion to break down the organic materials into small particles.
The decomposer instead consumes the remains produced by the scavengers.
Examples of decomposers can be bacteria and fungi.
Examples of scavengers can be animals (like insects, birds, little critters)
Explanation:
There is a large number of mitochondria in cardiac muscle cells because cardiac muscles need the mitochondria to:
1)work harder and longer.
2)maintain their shape.
3)maintain their color.
4)be attached to the ribs.
Answer:
to work harder and longer
Answer:
a. work harder and longer.
Explanation:
help!!!! i’ll give brainlest
Answer:
Lipids
Explanation:
Answer:
Lipids
Explanation:
All of the following describe outcomes of urbanization except
O decreased soil pollution
O food chain disruption in a natural habitat
O increased wastewater from sewage drainage
O loss of plant biodiversity
Answer:
O decreased soil pollution
Explanation:
Urbanization does not lead to decreased soil pollution.
Pollution is the introduction of contaminants into the environments. As urbanization progresses and the population of people in a place increases, soil pollution increases.
Also, industrial expansion causes increased production of wastes. So, some of these wastes find their way into the environment of which the soil is a main component. There is an increased amount of soil pollution.What is the name of this leaf
Answer:
A beam leaf
Explanation:
Make a claim about which organism(s) use carbon dioxide and which organisms) produced carbon dioxide. How did your test conditions affect the cycling of matter between plants and animals?
Evidence: Describe specific observations from your experiment to support your claim.
Reasoning: Did your observations support your claim? Describe, in detail, the connections between the evidence you gave and the claim you are making
Answer:
an organism is like a plant
What is the final step of the cell cycle, directly following mitosis?
Anaphase
Cytokinesis
Interphase
Metaphase
Answer:
Cytokinesis
hope it help u :) ✌❤
The stage of meiosis where the chromosomes do not move apart equally and cause chromosomal abnormalities is
Answer: anaphase
Explanation: Nondisjunction can occur during anaphase of mitosis, meiosis I, or meiosis II. During anaphase, sister chromatids (or homologous chromosomes for meiosis I), will separate and move to opposite poles of the cell, pulled by microtubules
Hope this helps :)
I need help please
Answer:
75 percent, 25 percent
Explanation:
How do simple diffusion and facilitated diffusion differ?
Answer:
Simple diffusion does not require energy: facilitated diffusion requires a source of ATP. Simple diffusion can only move material in the direction of a concentration gradient; facilitated diffusion moves materials with and against a concentration gradient.
Explanation:
What is a fixed allele?
O A. An allele that mutates with each generation
B. An allele that is found on many genes
C. An allele present in all members of a population
ОО
D. An allele that formed by adaptive radiation
Answer:
C. An allele present in all members of a population
Explanation:
Just took the quiz
A fixed allele is an allele that is present in all members of a population and has a frequency of 100%. Therefore, option (C) is correct.
What is an allele?An allele is a variant form of a gene that arises through mutation and is located on a specific location on a chromosome, known as a locus. Genes code for specific traits or characteristics, such as eye color or blood type, and alleles determine the variations of these traits.
For example, the gene that determines eye color has several different alleles, including blue, green, and brown, which produce different variations of the trait.
Alleles can be dominant, meaning that they are always expressed in the phenotype of an organism, or recessive, meaning that they are only expressed when paired with another recessive allele. The combination of alleles that an individual inherits from their parents determines their unique genotype and phenotype.
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Which of these is NOT an
example of insulator?
A. rubber pot holder
B. cloth curtains
C. aluminum foil
Answer:
ITS A Rubber pot holder
Explanation:
cauze rubber don't pass electricity...
Hope it helps :)
what is percentage of oxygen of inhaled air
Answer:
21%
I hope this helps!
What are the similarities and differences between the two karyotypes?
Answer:
The typical human karyotypes contain 22 pairs of autosomal chromosomes and one pair of sex chromosomes (allosomes). The most common karyotypes for females contain two X chromosomes and are denoted 46,XX; males usually have both an X and a Y chromosome denoted 46,XY.
Explanation:
a) Which country looks like it is experiencing exponential growth?
b) Which country looks like it has reached its carrying capacity?
c) Because it has reached its carrying capacity, describe the relationship between
its birth rates and death rates.
d) Describe what is happening to Europe's population size in terms of birth rates
and death rates.
e) Which country or countries could be experiencing:
emigration:
Explain your answer.
.
-immigration:
Explain your answer.
India has a sharp rising trend and a quickly growing population, so it appears to be growing exponentially. It seems that Japan's carrying capacity has been achieved.
How do population growth and carrying capacity relate to one another?Growing populations may be impacted by increased density in a given area. The greatest number of a species that an ecosystem can sustain is referred to as the carrying capacity of a region. Carrying capacity is based on the amount of resources available (food, habitat, water).
What are some examples of exponential population growth?The term for this quick trend of population rise is exponential expansion. The best illustration of exponential development is found in bacteria. Via prokaryotic fission, prokaryotes, such as bacteria, divide.
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Please answer it’s due at 4!!!!!!!!??
Answer:
sexual reproduction
Explanation:
Try not to say the time, because we are not the same time zone.
we are different countries;) lol
how would you determine the hardness of a mineral
Mohs Hardness Scale
Explanation:
A mineral's hardness is a measure of its relative resistance to scratching, measured by scratching the mineral against another substance of known hardness on the Mohs Hardness Scale.
What part of the cell allows the corona vīrus to enter?
Answer:
The cellular membrane
Explanation:
which indicator, when considered in conjunction with the ecological footprint, would provide the most information about environmental impact?
Human population would provide the most information about environmental impact.
Population- A population is the total number of people living in a certain region. The entire number of residents makes up a city's population. Residents or occupiers are the terms used to describe them. The population of an area consists of everyone who lives there.
Environment- The surroundings, things, or situations in which one finds oneself. The combination of biotic (living things) and abiotic (Non-lining) (temperature, soil, etc.) elements that affect an organism or ecological community and ultimately decide its shape and survival.
Organism- A living thing made up of one or more cells and able to carry on the activities of life (as using energy, growing, or reproducing)
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Which characteristic of sound makes it possible for bats to fly in the dark without hitting any objects?
Answer: echo location
Explanation:
How do enzymes support life functions of the cell and the body
Explanation:
Enzymes help speed up chemical reactions in the human body