Answer:
Biodiversity supports human and societal needs, including food and nutrition security, energy, development of medicines and pharmaceuticals and freshwater, which together underpin good health. It also supports economic opportunities, and leisure activities that contribute to overall wellbeing.
Explanation:
pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria
The primary goal of this study was to compare the pharmacokinetics profile of the medication free in solution with that of the parenterally administered, gelatine nanoparticles (CHN) containing cryptolepine hydrochloride for the treatment of malaria (CHS).
Via giving CHN or CHS (equal to 10 mg/kg of medication) by IV bolus injection into the lateral tail vein, single-dose pharmacokinetics was studied in Wistar rats. After delivery, the drug's plasma concentration was observed for 24 hours. In Wistar rats given a P.
berghei parasite challenge, chemopresor activity was examined. The intraperitoneal injection of either CHN or CHS at a dosage of 2.5–100 mg/kg/day was administered to the animals.
Giemsa-stained thin blood smears obtained on day four of infection were examined by light microscopy to gauge the amount of parasitaemia. It was discovered that CHN achieved a greater area under the curve (AUC (0-24)) compared to H CHS (by 4.5-folds).owever, CHS created a greater amount of dispersion (4-folds).
CHS had a lower (11.7 h) elimination half-life than CHN because of increased distribution and elimination rates (21.85 h). In comparison to CHS, CHN had greater chemosuppressive efficacy at all dosage levels due to its improved pharmacokinetic profile.
The molecule with the greatest chemosuppression (97.89 3.10) generated by 100 mg/kg of cryptolepine hydrochloride was loaded into gelatine nanoparticles, which enhanced both pharmacokinetics and in vivo antiplasmodial efficacy.
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What structure is responsible for increasing surface area to provide for the strength of attachment between the epidermis and dermis?.
Dermal papillae increase the strength of the connection between the epidermis and dermis.
Which form of collagen joins the dermis to the basal layer of the epidermis?The innermost layer of the epidermis, the stratum basale (also known as the stratum germinativum), connects it to the basal lamina, which is where the layers of the dermis are located. The basement membrane, a network of intertwined collagen fibers, which connects the cells of the stratum basale to the dermis.
The epidermis of thick skin has five layers stratum basale, stratum spinosum, stratum granulsum, stratum lucidum and stratum corneum.
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What happens when both left and right sternocleidomastoid muscles are contracted?.
This extension movement brings the head backward. A contraction of both SCM muscles can flex your neck, which brings your chin down in the direction of your breastbone. Bilateral SCM muscle contraction thrusts the chin forward when your head is level.
Which one should I choose? I’m not sure I’m correct! And be fast cuz its due in 15 mins
Answer: they release it into the atmosphere and soil
Explanation:
When plants die, the carbon goes into the soil, and microbes can release the carbon back into the atmosphere through decomposition.
Answer:
The answer is B
Explanation:
The answer is B because as the plants photosynthesize they absorb carbon dioxide from the atmosphere. when the plants die, carbon will go into the soil, and microbes will release the carbon back into the atmosphere through the decomposition stage.
Multicellular organisms are eukaryotes true or false
Answer:
false
Explanation:
Answer:
True because they have a nucleus
Convert 286,330,760,848.37 into scientific notation
Answer:
m x 10n, 1 ≤ m < 10 and n not for sure though
Explanation:
What are the major characteristics of Coelenterata
Amelia’s doctor says that she has a tapeworm. Which type of medicine is prescribed to Amelia?
Answer:
Antiparasitic srry if its wrong
Answer:
Nitazoxanide
Explanation:
Exponential growth(diagram A) refers to the phenomena of populations that double in size every generation. If you start with a single bacterium cable of dividing every 20 minutes,how many bacteria would you have after just four hours
After four hours you would have about 4096 bacteria.
Since the bacteria undergoes exponential growth, After each generation the population number doubles in size.
Hence, at the end of first 20 minutes we will have two bacteria.
at the end of 40 minutes we have 4 bacteria and at the end of one hour we have 8 bacteria and so on.
since the bacteria undergoes binary fission, a simple way to calculate the total number of bacteria is to divide the 4 hours in parts of 20.
In four hours the bacteria multiplies 12 times
hence, 2^12=4096.
What is exponential growth?
The exponential phase of growth is a balanced growth pattern in which all the cells regularly divide by binary fission and increase in size by geometric progression. Depending on the make-up of the growth medium and the incubation circumstances, the cells divide at a consistent rate.
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Small-island developing states have long been at the forefront of demanding that countries that are industrially advanced and are largely responsible for the emissions that cause climate change must address the loss and damages that sids are encountering due to climate change. What is the current status of reparations for sids?.
(c) "Industrialized countries have not made a legally binding commitment to provide reparations to SIDS for their losses and damage" is the current status of reparations for sids.
Small island developing states (SIDS) are a special class of nations that contribute very little to the causes of climate change yet endure a disproportionate amount of its effects. For the foreseeable future, there are serious concerns about how vulnerable they are and how little they have to change.
This policy brief examines both the obstacles to adaptation and development, internal migration and displacement, sovereignty, and exclusive economic zones that SIDS face as a result of climate change, as well as the strategies they employ to advance their cause, such as monetary compensation claims and multilateral diplomacy.
The policy brief suggests a course of action that outlines potential political, legal, economic, and other approaches to resolving the SIDS' situation. In order to compensate SIDS for their losses and damage, industrialized nations have not established a legally enforceable promise to do so.
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Question correction:
Small-Island Developing States have long been at the forefront of demanding that countries that are industrially advanced and are largely responsible for the emissions that cause climate change must address the loss and damages that SIDS are encountering due to climate change. What is the current status of reparations for SIDS?
a. Industrialized countries have indicated that they do not believe that reparations for loss and damages are warranted.
b. After having legally committed to reparation commitments in the Paris Agreement, industrialized countries are 5 years into paying reparations.
c. Industrialized countries have not made a legally binding commitment to provide reparations to SIDS for their losses and damage.
d. Industrialized countries have made a legally binding commitment to provide reparations to SIDS for their losses and damage
According to the rna world model, a ribozyme would replicate by creating a double-stranded rna intermediate. Would you expect the intermediate to have the same catalytic activity as the original ribozyme?.
According to the RNA world model, a ribozyme would replicate by creating a double-stranded RNA intermediate, but the intermediate will not have the same catalytic activity as the ribozyme.
Ribozyme is the RNA that has the ability to catalyze chemical reactions. A ribozyme can replicate to form double stranded RNA intermediate.
However, it does not have the same catalytic activity because the activity depends upon the tertiary structure of a RNA. And the intermediate will not have the same tertiary structure as ribozyme. It will have entirely different bonds and active sites. Hence the intermediate may not have catalytic activity.
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Correctly identify the following labels on the plant and animal cells.
Answer:
А Plasma membrane (Cell membrane)
B Cell wall
C Cytoplasm
D Vacuole
E Nucleus
F Chloroplast
H Mitochondria
G No idea sorry
I endoplasmic reticulum
J Golgi apparatus
Explanation:
Sorry for G ask your teacher but this look like nothing
If you hold a salty cracker in your mouth long enough, it will begin to taste sweet. What is responsible for this change in taste?.
The transformation of starch into sugar starts withinside the mouth. Amylase is an enzyme in saliva with a view to ruin-down starch to sugar. If an man or woman chews on a saltine cracker for a while, it'll start to flavor candy due to the fact the enzymes in saliva ruin down the starch into glucose sugar
Nerves located alongside the pathway from the mouth to the mind are liable for flavor bud characteristic and the notion of flavor. Nerve harm everywhere alongside this pathway, whether or not from damage or illness, can make contributions to a alternate to your flavor buds
Within the saliva, there's an enzyme referred to as amylase that breaks down carbs. Specifically, it breaks down starch molecules and turns them into easy sugars. If a cracker tastes candy, this is due to the fact the amylase is breaking down the carbs.
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What are "old growth" forests?
Forests that were planted by original peoples
Forests located in grasslands
Forests that have never been cut
Forests that burn easily
"Old growth" forests are the forests which have never been cut and is denoted as option C.
What is Forest?This is referred to as an area which has large population of trees present in the area and they form canopies thereby serving as a habitat for some forms of organisms.
The trees present in the ecosystem are referred to as the primary producers and they undergo photosynthesis to ensure that energy is available to other organisms. "Old growth" forests as the name implies is the type of forest which is very old and has reached its climax due to it not being cut.
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(Brainliest) please help!!!
Which of the following statements is true concerning diabetes?
A. Type 1 diabetes develops with the body doesn't make insulin or use it properly in
the body
B. Type 2 diabetes is often linked to obesity and presents itself when body cells
stop responding properly to insulin
C. People who have diabetes can usually manage and control it with a healthy diet,
exercise and insulin injections
D. All the above
Answer: D. All the above
People of all ages can develop type 1 diabetes. If you have type 1 diabetes, your pancreas doesn't make insulin or makes very little insulin. Insulin helps blood sugar enter the cells in your body for use as energy. Without insulin, blood sugar can't get into cells and builds up in the bloodstream.
Type 2 diabetes occurs when the body doesn't produce enough insulin to function properly, or the body's cells don't react to insulin. This means glucose stays in the blood and isn't used as fuel for energy. Type 2 diabetes is often associated with obesity and tends to be diagnosed in older people.
Two single-celled organisms are shown.
Which statements accurately compare the two organisms?
Select TWO correct answers.
Answer:
Explanation:
The first image is a eukaryote cell since it has a nucleus. The second is a prokaryote cell because it does not have a nucleus, so it is a germ or any other organism that does not contain a nucleus.
One of the single-celled organisms is a eukaryote and the other is a prokaryote.
What are prokaryotes and eukaryotes?Prokaryotes and eukaryotes are the two categories into which all cells on Earth may be categorized. Prokaryotes can be either bacteria or archaea, and are always unicellular creatures.
Eukaryotes are made up of eukaryotic cells, which can be unicellular or multicellular and include plants, animals, fungi, and protists.
Prokaryotic cells are substantially smaller and less complicated than eukaryotic cells, which also lack a number of cell structures and organelles.
Both prokaryotes and eukaryotes are different sorts of cells; in fact, they are the only two. Prokaryotic species, which might be either bacteria or archaea, are invariably unicellular.
Therefore, the first organism is a eukaryote and the second is a prokaryote.
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imasheva ag, bosenko dv, et al. (1999) the effect of three ecological stresses on variation of morphological traits in drosophila melanogaster. russian journal of genetics, 35(10), 1188–1193.
The phenotypic and genetic variance in morphological features (thorax length, wing length, number of sternopleural and abdominal bristles, and number of arista branches) was investigated in Drosophila melanogaster in relation to temperature, diet, and density stressors.
Additionally, the impact of stress on the stability of bilateral characteristics' fluctuation asymmetries was examined.
It has been demonstrated that all pressures lead to an increase in phenotypic variance and variable bilateral trait asymmetry. Under stressful circumstances, genetic diversity of morphometric features evaluated using the isofemale line approach was greater than under regular circumstances.
The impact of biotic and abiotic pressures on genetic and phenotypic diversity was comparable. Stress typically had a greater impact on morphometric trait variability than it did on meristic trait variability.
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Microfilaments can be involved in contractions that change the shape of a cell when they are.
Microfilaments can be involved in contractions that change the shape of a cell when they are associated with motor proteins such as myosin.
Microfilaments- As they are made up of two entangled strands of the globular protein know as actin, microfilaments are also known as actin filaments. They are the tiniest filament of the cytoskeleton and polymers of a protein actin. They are essential for muscle contraction, cell division, and cellular mobility.
Myosin- The molecular motor known as myosin transforms the chemical energy supplied by ATP into mechanical energy. The actin filaments are subsequently pulled along by this mechanical energy, contracting the muscle fibers and resulting in movement.
The given question is incomplete, find below the complete question,
Q. Microfilaments can be involved in contractions that change the shape of: -
a cell when they are
a. Working with microtubules to bend cilia and flagella
b. Associated with motor proteins such as myosin
c. Complexed with intermediate filaments to form desmosomes
d. Being assembled from actin monomers
e. Associated with actin-associated proteins that are adding actin monomers to the "plus end" of the filament
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Our blood is mostly water.blood has the most important job of circulating nutrients and ions every cell in our body. the only reason blood is able to do this is because
Saturated and unsaturated fats differ from each other in what important structural way?.
Differ from each other are saturated fats have the maximum number of hydrogens possible, while unsaturated fats have a double bond between two of the carbons.
The ideal number of bonds for a carbon is four.Each carbon atom in saturated fats is linked to four hydrogen atoms. It has a straight structure as a result, allowing them to stack on top of one another. They are solid at normal temperature so they can stack. As a result, they can clog your arteries because they are solid in your body.Carbon in unsaturated fats forms a double bond with another carbon. Since the molecule has a bent structure due to the double bond, it can't stack on top of itself and is liquid at ambient temperature. These fats are better for you.To learn more about fats.
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PLEASE HELP ME!
Of the five characteristics of living things, which one is required for the species to survive but does not have to apply to an individual?
response to the environment
use of energy to function
reproduction
growth and change over a life cycle
Answer:
I think its 'growth and change over a life cycle', im not the best at biology :/
The central sulcus is associated with the part of the brain that controls conscious movement of the opposite side of the body. Because of this it is also known as?.
Answer:
The Rolandic sulcus, also called Rolando or the central sulcus
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What are the three
groups of
biodiversity?
A. bacteria, fungus, algae
B. species, ecosystems, genes
C. kingdoms, domains, DNA
D. individuals, living, non-living
Answer:
B. Species, ecosystems, genes
Destruction of the rain forests will lead to global warming because:
HELPPPPPPPPP PLEASE WILL GIVE BRAINLIEST
Prior to cell division, each chromosome must__13_. Each of these copies
is called a ___14___ and they are held together in an area called a ____15___
answer:
coiled/replicate, recombinant, centromere
Explanation:
Polydactylism occurs _______. a. only in cats b. only in humans c. in less than one in 1000 children d. more commonly in certain populations, such as the amish. please select the best answer from the choices provided a b c d
Answer: d.
more commonly in certain populations, such as the Amish.
Explanation:
Hi. Help with question number 1.
The patterns of motion of two different objects include the following: circular and periodic motions.
What is motion?Motion is defined as the change in position of an object either at a place or from one place to another.
Two or more different objects can exhibit different patterns of motion which include the following:
Circular motion: This is defined as the movement of an object along a circular pathway.
Examples of objects in a circular motion include the following:
Planets Revolving Around the Sun. The sun rotates about its own axis while the planets revolves round about it.Satellites Orbiting Around Planets.Stone Tied to a String.Periodic motions: This is defined as the motion of a object which repeats itself after a certain period of time. A typical example is the motion of the simple pendulum.
In the two types of motions discussed, it would be observed that two objects has different patterns of motion.
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What two main things do eurkaryotes have that prokaryotes lack?
Answer:
Nucleus and organelles
- burn causes accumulation of cd11bf4/80 macrophages in periphery. expression of tlr2 and tlr4 increases in these macrophages early (3 days) after burn and decreases late (14 days). when tlr2 and 4 are ligated and macs are stimulated, there’s difference in cytokine expression profile, but it changes when either tlr2 or 4 are stimulated. (cairns 2008
After burn injury, complicated altered cytokine profiles are caused by toll-like receptor 2 and 4 ligation. Toll-like receptor TLR2 and TLR4, expressed on innate immune cells, are important mediators of the immune response to pathogens.
Background:
In this study, we hypothesized that burn injury would lead to altered cytokine secretion profiles following her TLR2 or TLR4 ligation, associated with changes in her TLR expression in innate immune cells.
METHODS:
Female C56BL/6 mice were subjected to full-thickness burns or sham wounds of her 20%. At 3 or 14 days after her injury, whole spleen cells or purified splenic macrophages were cultured with her TLR2 ligand peptidoglycan or her TLR4 ligand lipopolysaccharide.
Supernatants were tested for TNF-α, MCP-1, IL-6, and IL-10. Cell death was assessed using flow cytometry. CD11b F4/80 congenital macrophages were sorted 14 days after burn injury and TLR2 and 4 expression was determined by quantitative reverse transcriptase polymerase chain reaction and flow cytometry.
RESULTS:
Burn injury results in a stable accumulation of CD11bF4/80 macrophages in the periphery. Purified macrophages early after burn injury upregulated TLR2 and 4, followed by a decrease in TLR2 and TLR4 expression late after burn injury.
Equivalent numbers of TLR2 and TLR4 ligated purified macrophages 3 days after thermal injury revealed no significant difference in cytokine secretion compared to sham. Stimulation 14 days after burn injury showed a significant decrease in tumor necrosis factor-α secretion by macrophages compared to sham mice.
In contrast, in the late post-burn period, interleukin-10 was significantly increased (mean approximately 1.8-fold) after either TLR2 or TLR4 stimulation. Interleukin-6 and monocyte chemoattractant protein-1 secretion were unchanged from sham levels.
In contrast, stimulation of whole splenocytes increased cytokines 3 and 14 days after burn injury. This effect may be caused by the accumulation of His TLR macrophages, which are resistant to TLR-induced cell death.
CONCLUSIONS:
Cytokine secretion profiles after TLR2 and TLR4 ligation after burn injury are altered in ways that do not clearly reflect anti- or pro-inflammatory states and are associated with intrinsic changes in populations. TLR2 and TLR4 ligation play complex and diverse roles in mediating the immune response to burn injury.
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