yablon sa, brashear a, gordon mf, et al. formation of neutralizing antibodies in patients receiving botulinum toxin type a for treatment of poststroke spasticity: a pooled-data analysis of

Answers

Answer 1

In this group of people with post-stroke spasticity in three 12- to 42-week clinical trials who had >/=1 therapy with a particular BoNTA formulation at doses spanning from 100 to 400 U, the formation of NAbs was uncommon (1/191).

What is Spasticity?

Spasticity is a characteristic of altered skeletal muscle function along with  paralyzing, enhanced tendons reflex activity, and increased tone. Its name comes from the Greek word spasms, which means "drawing, pulling." It is also known as an unusual "tightness," "stiffness," or "pull" of muscles in everyday speech.

Clinically speaking, spasticity is the result of excessive velocity-dependent muscular contraction brought on by the motor neurons' loss of inhibition. In the end, this results in hyperreflexia, which is an accentuated deep tendon reflex. The medication baclofen, which works as an agonists at inhibitory GABA receptors, is frequently used to treat spasticity.

The most prevalent type of cerebral palsy, that is a collection of persistent movement issues that do not become worse with time, is spastic cerebral palsy. Baclofen's effectiveness as an anti-spasticity medication is influenced by the inhibiting effects of GABA.

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Related Questions

What does abiotic mean?
A. living
B. synthetic
C. non-living
D. polymer-based​

Answers

Answer:

C

Explanation:

Non Living I Belive  

Answer:

i think it is letter C

Explanation:

Differences between epithelial and meristematic tissue.​

Answers

Answer: Epithelial tissue is the internal and external lining of the surfaces of organs. Connective tissue connects tissues and organs.

Explanation: Good Luck!

Answer:

1. A tissue which covers body surfaces such as lining of organs and skin, and tissue which plays role in secretion, protection and absorption is referred as Epithelial tissue.

A tissue which is composed of fibers, water, and adhesion proteins and which connects parts of body together, this is referred as Connective tissue.

2.It lines organ surfaces, the cavity, and blood vessels of the animal body.

It connects, and supports different organs and tissue in the body.

What type of macromolecule is an enzyme?

carbohydrate
lipid
protein
nucleic acid

Answers

A protein is an enzyme. The monomer for a protein is an amino acid. There are 20 types of amino acids. Most proteins are made of amino acids only.

the capacity of a brain area to develop new neural pathways as it adjust to good and bad experinces is known as

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The capacity of a brain area to develop new neural pathways as it adjust to good and bad experiences is known as Neuroplasticity.

Neuroplasticity also known as brain plasticity is defined as the ability of the nervous system to change its function and develop new pathways in response to new information.

Neuroplasticity is the changes that happen to the brain over the years. These changes depend on the new experiences which can be good or bad. It also depends on environmental influences, practice, and psychological stress.

Neuroplasticity play an important role for healthy development, learning, memory.

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The capacity of a brain area to develop new neural pathways as it adjusts to good and bad experiences is known as neuroplasticity

Neuroplasticity is a broad term related to the brain's capacity to alter, modify, and adapt its function and structure across people's lives and in response to stimuli.

Individual differences in brain function and structure contribute to the variability observed in neuroplasticity mechanisms, which also show significant differences across individuals. Indeed, a growing body of recent research indicates that the guidelines and mechanisms governing cortical plasticity seem more dynamic than previously thought.

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What phase of the cell cycle does DNA replication occur?

a
G1
b
S
c
G2
d
M
e
cytokinesis

Answers

Answer:

s phase

Explanation:

so the genetic material can double before it begins division

Why were garden peas a good choice for a study of heredity?

Answers

Answer:

pea plants because they were easy to grow, could be bred rapidly, and  several observable characteristics, like petal color and pea color.

Explanation:

4. What is an energy pyramid? Why is there a loss of energy at each level
moving up?

Answers

Answer:

#1 An ecological pyramid is a graphical representation designed to show the biomass or bioproductivity at each trophic level in a given ecosystem.  And #2 Most of the food energy that enters a trophic level is "lost" as heat when it is used by organisms to power the normal activities of life. Thus, the higher the trophic level on the pyramid, the lower the amount of available energy.

Explanation:

At what stage of human development would you expect to first see a beating heart?
Choose 1 answer:
Choose 1 answer:

(Choice A)
A
Zygotic stage

(Choice B)
B
Blastocyst stage

(Choice C)
C
Embryonic stage

(Choice D)
D
Fetal stage

Answers

at what stage of human development wuold you exept to first see abeating heart? the answer is ç

The stage of human development that is expected to first see a beating heart is the embryonary stage  (Option C).

The heart of an embryo starts beating at approximately week 5 of pregnancy.

The first two weeks of human development after conception is called the germinal stage, whereas the stage of development lasting from the third until the eighth week of pregnancy is called the embryonic stage.

This stage (embryonic stage) starts once the zygote is implanted in the uterine wall.

In conclusion, the stage of human development that is first expected to see a beating heart is the embrionary stage  (Option C is correct).

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The effect of population distribution and density on the environment and natural resources is known as.

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The effect on the environment and the natural resources by population distribution and density is termed Carrying capacity.

Carrying capacity refers to a species' average population size in a particular habitat. The environment can regulate a species' population size by providing enough food, shelter, water, and mates. If these needs are not met, the population will decrease until the resource is replenished.

Population composition can be characterized by the pattern produced by age distribution and gender ratio at different scales and locales. The population's distribution and density both show the influence of demographic composition.

Hence, the effect of population on its environment is called as carrying capacity as this will tell us that for how long will the environment be able to sustain that population size.

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What is the per capita growth rate of a population of 250, with 50 births and 80 deaths in a year?

Answers

The population will decrease by 30 every year this maybe wrong. If it is and you can specify more on the question I’d love to help.

which organelle builds proteins

Answers

Answer:

I belive its ribosomes.....

Explanation:

If an atom has an atomic number of 16, the number of electrons it would
have in its outer most shell would be

Answers

Hello it’s b bbbbbbb

Answer: PHOSPHORUS

Explanation:

The term atomic number, conventionally denoted by the symbol Z, indicates number of protons present in the nucleus of an atom, which is also equal to the number of electrons in an uncharged atom. The number of neutrons is represented by the neutron number (N)

im new to this so i tried what i knew

SOMEONE PLEASE HELP ME WITH THIS PLEASE PLEASE PLEASEE!!!!!

Answers

Answer:

The answer is D

Explanation:

Answer:

The answer is A.

❤ I hope this helps you, ma'am/sir/whatever your pronouns are! ^w^ ❤

environmental factor in fresh water, ocean trench, hot springs, terrestrial and problems caused for each ​

Answers

Answer:

sorry don't know but I need points plese mark me as brainlest

Explanation:

I want free points

What would happen if sulfur was removed entirely?

Answers

Sulfur is essential for humans, animals and plants. When it enters our body, it can be incorporated into tissues such as skin and cartilage. It is also found in some proteins and vitamins. if the sulfur were completely removed, it causes several symptoms, such as depression, neuritis, unpleasant odor in the saliva and a decrease in the brightness of the skin. To avoid this deficit, it is recommended to eat fruits and vegetables. Foods of animal origin such as milk and eggs also have it in their constitution.

What is the role of sulfur in the human body?

Another great advantage of sulfur is that it has anti-inflammatory action, in addition to being an antioxidant. This means that it fights free radicals and also increases the body's defense against invading agents, preventing, for example, the flu. In addition, the mineral helps to detoxify the body.

With this information, we can conclude that Sulfur dioxide is a toxic gas that mainly affects the mucous membranes, acting on the respiratory system and eyes, causing irritation.

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Which part of the mollusk body is specialized for burrowing,feeding , and movement

Answers

Answer:

The foot

Explanation:

Mollusks have bilateral symmetry and are coelomed protostomes, but the coelom is only represented by small residual spaces around the pericardial cavity, the gonads, some parts of the nephridia, and in some cases part of the intestine. The foot is used primarily as a means of movement. The foot is also a very important structure, although it has adapted differently depending on the classes of mollusks. It is characterized by having a really powerful and complex musculature. The most widespread use of this organ is that of locomotion, as happens with gastropods. However, in bivalves it serves to burrow or in cephalopods it helps to provide propulsion.

Invertebrate animals with the unsegmented soft body which is enclosed in shells made up of calcium carbonate are called Mollusca.

The part of mollusk's specialized in feeding, burrowing and movement are:

Foot

The Mollusca can be explained as:

The Mollusca have the bilateral type of symmetry and coelomate protostomes which are visible as residual spaces surrounding the pericardial cavity, nephridia and gonads.

The foot is the part that is used in locomotion and is adapted differently for various purposes in various forms of Mollusca.

It has a complex musculature and helps in propulsion, as a mode of feeding appendage and in some for burrowing purposes.

Therefore, the foot is a specialized organ.

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what directs the action of every cell in your body

Answers

Answer:

the nucleus of the cell

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The cell membrane has____. a) polar heads on the outside and nonpolar fatty acids on the inside b) nonpolar fatty acids on the outside and a polar heads on the inside c) polar heads on both inside and outside d) nonpolar fatty acids on both inside and outside

Answers

Answer:

a) polar heads on the outside and nonpolar fatty acids on the inside

Explanation:

The cell membrane is made up of phospholipids arranged in a bilayer, where hydrophilic polar (negatively-charged) heads of phospholipids interact with water molecules (i.e., aqueous surrounding media). Moreover, non-polar (uncharged) fatty acid tails are hydrophobic because they cannot be dissolved in water. Thus, the bilayer cell membrane is a structure where non-polar fatty acid chains are localized in the inner region (away from the water), while hydrophilic phosphate heads face outward, interacting with water on both sides of the cell membrane.

A order arrangement of properties is called

Answers

Answer:

its order of operations

Ecological succession are the natural gradual changes in the types of species that live in an area we may refer to ecological succession as either primary or secondary the graphic represents an example of primary succession which begins in an area that has no living organisms present. notice in the illustration the first organisms to inhabit the area undergoing succession are lichens and Moss. what a biotic feature restricts the growth of more diverse plants in this area.​

Answers

Answer:

The lack of topsoil inhibits the growth of more diverse organisms in the region.

Explanation:

Following catastrophic or destructive events, primary succession occurs with the growth of the microorganisms. Here a non-habitable area is exploited by a colonizing organism.  For instance, lichens and moss break down rock and decompose to add nutrients to sediment creating topsoil.

Ultimately, these make the environment more livable by nutrient cycling, weathering, etc., which ushers in secondary succession. Here over time, the cultures become more dynamic, more diverse and an ever-larger food web.

In the first stage of primary succession after there has been a volcanic eruption, the soil quality will be poor. Plants that are good soil formers, such as lichens and moss, will improve the soil. Over time, with increasing plant diversity, rich soil with humus will form that will improve water retention. Taller and more diverse plants will allow for more filtered sunlight and more moderate soil temperatures.

which is a true statement regarding metastasis? group of answer choices increased cell-to-cell adhesion helps metastasis. lack of proteases and collagenases aids in metastasis. cells must first escape the basement membrane of tissue. penetration of the basement membrane of the vessel occurs first.

Answers

The correct option is (C) cells must first escape the basement membrane of tissue.

The process through which cancer spreads is described as "metastasis."

What is metastatic cancer?Unlike normal cells, cancer cells have the ability to spread outside of the area of your body from which they originated. These conditions are referred to as metastatic cancer, advanced cancer, or Stage IV cancer. Tumor cells must first exit the basement membrane of the tissue of origin, migrate through the extracellular space, and then pierce the basement membrane of the vessel in order to reach the blood or lymphatic circulation.Metastatic cancer may occasionally be cured. However, for the majority of metastatic malignancies, medication can lessen symptoms while also slowing the spread of the disease. Even after the onset of metastatic disease, several cancer types can be managed for many months or even years.

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One half of a duplicated chromosome is called:
Telomere
Chromatid
Chromatin
Centromere

Answers

The Answer is Chromatid

One half of a duplicated chromosome is called Chromatid. The correct option is B.

Thus, A chromatid is the name for the duplicated half of a chromosome. The chromosome is duplicated during DNA replication, creating two identical copies known as sister chromatids.

The centromere, a particular area, is what holds these sister chromatids together. A complete set of DNA molecules or genetic material can be found in each chromatid. During cell division, the sister chromatids split apart to form individual chromosomes, which are then dispersed to the daughter cells.

Contrarily, the telomeres are specialized structures found at the ends of chromosomes that aid in maintaining the DNA's integrity during replication and guard against deterioration.

Thus, One half of a duplicated chromosome is called Chromatid. The correct option is B.

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label the internal anatomy of a finger.

Answers

The correct answer is number quadrant level c

preclinical alternative model for analysis of porous scaffold biocompatibility applicable in bone tissue engineering

Answers

A promising method for repairing critical-size bone lesions is the use of scaffolds with the proper porosity. For the creation and mending of bones, vasculization is necessary. In this study, chitosan and polyhydroxybutyrate (PHB)-based porous biopolymer scaffolds are used to evaluate angiogenesis.

What is Tissue engineering ?

Using a combination of cells, engineering, materials techniques, and appropriate biochemical and physicochemical parameters, the biomedical engineering field of tissue engineering can repair, maintain, enhance, or replace several types of biological tissues.

Skin, cartilage, bone, heart valves, and bladder are just a few examples of tissue engineering that are now being used in therapeutic settings. Numerous further examples, including as artificial livers, pancreas, and blood arteries, are still being studied and tested on animals.

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An increase in the membrane permeability for a solute will result in an increase in the driving force for diffusion of that solute through the membrane. True or false?.

Answers

A membrane's permeability has an impact on the diffusion rate. As membrane permeability increases, the diffusion rate rises.

The dispersion of materials is also impacted by changes in temperature and pressure values.The passive diffusion rate of penetrated molecules through the biomembrane can be used to quantify a membrane's permeability. It is well acknowledged that the permeability of any particular molecule depends mostly on its size, polarity, charge number, and molar mass.The capacity for materials to flow into and out of a membrane is known as permeability. The ease with which a chemical can diffuse across a cell membrane determines its permeability.Only chemicals that can dissolve in fat can typically pass through a cell membrane.The electrical potential gradient across the cell membrane and the concentration gradient of the permeant ion across the membrane together make up the net electrochemical driving force.

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cellular energy, most often in the form of atp, is required to move substances across cell membranes in which one of these processes?

Answers

Active Transport is the mechanism by which molecules are moved across cell membranes.

It requires cellular energy which most frequently is in the form of ATP.

What is Active Transport?

Active transport is the process of movement of substances from a lower concentration to a higher concentration, i.e., against the concentration gradient,  with the expenditure of energy in the form of ATP. Active transport occurs against the concentration gradient while other transport processes like diffusion facilitated diffusion and osmosis occur along the concentration gradient and without the involvement of ATP.

Thus, cellular energy is required in the process of active transport to move substances across cell membranes. And, ATP is the most frequently used energy in this process.

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Which is not a function of cholesterol within the cell membrane?

Reduces permeability to some solutes

Reduces membrane fluidity

Prevents crystallisation of the membrane at low temperatures

Transports molecules across the cell membrane

Answers

Answer:

c

Explanation:

The function of cholesterol within the cell membrane maybe be many, but does not include the reduction in membrane fluidity .

The steric structure of the cholesterol in the cell membrane is such that:

it prevents freezing of the membrane when the temperature gets lowIt limits the permeability of some materialsit makes the membrane more fluid and stableit helps take up cholesterol from the surrounding environment into the cell, hence, helps with the transport of molecules.

The correct answer as to which is not a function of cholesterol within the cell membrane would, therefore, be that it reduces membrane fluidity.

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the epigastric region is a portion of the cavity. multiple choice pelvic pleural vertebral abdominal

Answers

The epigastric region is a portion of the abdominal cavity.

The correct option is d.

The greatest hollow area in the body is the abdominal cavity. Its lower limit is the upper plane of the pelvic cavity, and its upper barrier is the diaphragm, a sheet of muscle and connective tissue that divides it from the chest cavity. The spinal column, as well as the abdomen and other muscles, encircle it vertically.

The epigastrium is the top portion of your abdomen that is immediately below your rib cage. The epigastrium houses your pancreas and the duodenum, a section of your small intestine. Additionally, your stomach and liver are partially located here.

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Theres an old man needed your help but you are soo late in your work.What would you do?explain it briefly.​

Answers

Answer:

I will help him first

Explanation:

because it's our duty to help elders .

Where does an action potential occur? Explain the process of what occurs inside the axon (the membrane) as the action potential is traveling down the axon.

Answers

Hi how do I answer there’s no web
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